Description

Spiro[4.4]Nonane-1,6-Diamine, (1S,5S,6S)- (9Ci) is a high-purity, stereochemically defined chiral diamine building block. This compound matters as a sophisticated intermediate for the synthesis of complex molecules, offering a rigid, three-dimensional spirocyclic scaffold that can impart unique conformational and steric properties to target compounds. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis, ligand design, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.
• Asymmetric Catalyst Ligand: Used in the design and preparation of chiral ligands for transition metal catalysis, enabling enantioselective transformations critical for efficient API manufacturing.
• Agrochemical Synthesis: Serves as a precursor for developing new, stereochemically pure active ingredients with potentially enhanced efficacy and environmental profiles.
• Advanced Material Research: The rigid spirocyclic structure makes it a candidate monomer for constructing specialty polymers, dendrimers, or metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and tools to study biological systems and enzyme mechanisms.

Basic Information

Product Name	Spiro[4.4]Nonane-1,6-Diamine, (1S,5S,6S)- (9Ci)
CAS No.	832747-54-3
Molecular Formula	C9H16N2
Molecular Weight	152.24 g/mol
Synonyms	(1S,5S,6S)-Spiro[4.4]nonane-1,6-diamine; (1S,5S,6S)-1,6-Diaminospiro[4.4]nonane; (1S,5S,6S)-Spirobicyclononane-1,6-diamine; (1S,5S,6S)-1,6-Diaminospiro[4.4]nonane; (1S,5S,6S)-Spiro[4.4]nonane-1,6-diyldiamine; (1S,5S,6S)-rel-Spiro[4.4]nonane-1,6-diamine; Chiral Spiro[4.4]nonane diamine; (S,S,S)-Spirodiamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide high-purity material suitable for research and development, with typical purity levels exceeding 97% (by HPLC). Identity is confirmed via spectroscopic methods (NMR, IR, MS). Certificates of Analysis (COA) detailing chiral purity (enantiomeric excess), assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, we recommend keeping the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.