Description

(2E)-1-[3-(Difluoromethoxy)Phenyl]-3-(Dimethylamino)Prop-2-En-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its specific α,β-unsaturated ketone (enone) structure. This compound is critical for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architecture. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of target drug molecules, especially those with a difluoromethoxy phenyl moiety.
• Agrochemical Research: Used in the development and scale-up of novel pesticides and herbicides, leveraging its unique fluorinated structure.
• Chemical Synthesis: Acts as a versatile Michael acceptor or electrophile in organic synthesis for creating complex molecular frameworks.
• Material Science: Potential application in the research of specialty polymers and advanced organic materials.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	(2E)-1-[3-(Difluoromethoxy)Phenyl]-3-(Dimethylamino)Prop-2-En-1-One
CAS No.	832741-15-8
Molecular Formula	C₁₂H₁₃F₂NO₂
Molecular Weight	241.24 g/mol
Synonyms	1-[3-(Difluoromethoxy)phenyl]-3-(dimethylamino)-2-propen-1-one; (E)-1-[3-(Difluoromethoxy)phenyl]-3-(dimethylamino)prop-2-en-1-one; 3-(Dimethylamino)-1-[3-(difluoromethoxy)phenyl]-2-propen-1-one; (E)-3-(Dimethylamino)-1-[3-(difluoromethoxy)phenyl]prop-2-en-1-one; N,N-Dimethyl-1-[3-(difluoromethoxy)phenyl]-3-oxo-2-propen-1-amine; Difluoromethoxy Chalcone Derivative; 832741-15-8; Enone Intermediate 832741-15-8
EINECS	Contact for details

Quality Control

Our (2E)-1-[3-(Difluoromethoxy)Phenyl]-3-(Dimethylamino)Prop-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.