Description

3-Cyclopropyl-2-Thioxo-1,3-Diaza-Spiro[4.5]Decan-4-One is a sophisticated spirocyclic thiourea derivative, a key structural motif valued for its unique three-dimensional geometry and functional group reactivity. This compound serves as a critical high-purity building block and pharmacophore in advanced organic synthesis, enabling the development of novel molecules with targeted properties. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A versatile scaffold for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, infectious diseases, and metabolic conditions.
• Agrochemical Research: Used as a precursor in the development of new herbicides, fungicides, and insecticides, leveraging its spirocyclic structure for enhanced bioactivity.
• Chemical Biology Probe: Serves as a core structure for designing enzyme inhibitors or receptor modulators to study biological pathways and target validation.
• Material Science: Potential application as a monomer or additive in the synthesis of specialty polymers with specific thermal or mechanical properties.
• Catalyst Ligand Synthesis: The thiourea and spirocyclic components can be utilized to develop novel chiral or non-chiral ligands for asymmetric catalysis and metal complexation.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic synthesis, including cyclization reactions and heterocycle formation.

Basic Information

Product Name	3-Cyclopropyl-2-Thioxo-1,3-Diaza-Spiro[4.5]Decan-4-One
CAS No.	832741-02-3
Molecular Formula	C12H17N3OS
Molecular Weight	251.35 g/mol
Synonyms	3-Cyclopropyl-2-thioxo-1,3-diazaspiro[4.5]decan-4-one; 1,3-Diaza-2-thioxo-3-cyclopropylspiro[4.5]decan-4-one; Spiro[cyclohexane-1,3'-[3H]imidazo[1,5-a]indol]-8'(1'H)-one, 1'-cyclopropyl-1',2',3',5',6',7'-hexahydro-2'-thioxo- (9CI); 1'-Cyclopropyl-1',2',3',5',6',7'-hexahydro-2'-thioxospiro[cyclohexane-1,3'-[3H]imidazo[1,5-a]indol]-8'(1'H)-one; 832741-02-3; Aurora KA-17637; AKOS005258156; ZINC000257830587
EINECS	Contact for details

Quality Control

Our production of 3-Cyclopropyl-2-Thioxo-1,3-Diaza-Spiro[4.5]Decan-4-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All materials are characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity determination by chromatographic techniques. A Certificate of Analysis (COA) detailing all critical quality attributes is provided with each shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.