Description

4-Methyl-6-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-3-ylamine is a high-value, nitrogen-rich heterocyclic building block featuring a trifluoromethyl group, which imparts unique physicochemical properties. This compound is critical for advanced research and development, particularly in the pharmaceutical and agrochemical sectors, where its scaffold is prized for creating novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists working on new active ingredients, such as kinase inhibitors and crop protection agents.

Application

• Key synthetic intermediate in the research and development of pharmaceutical candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Advanced building block for constructing novel agrochemicals, including herbicides, fungicides, and insecticides, leveraging the stability of the trifluoromethyl group.
• Precursor in material science for the synthesis of specialized organic electronic materials and ligands for catalysis.
• Versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies due to its fused pyrazolopyridine core.
• Used in custom synthesis and contract manufacturing for process development and scale-up projects.

Basic Information

Product Name	4-Methyl-6-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-3-ylamine
CAS No.	832740-69-9
Molecular Formula	C8H7F3N4
Molecular Weight	216.16 g/mol
Synonyms	4-Methyl-6-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-3-amine; 3-Amino-4-methyl-6-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine; 6-(Trifluoromethyl)-4-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine; 832740-69-9; 4-Methyl-6-trifluoromethyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine; 4-Methyl-6-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-3-amine; 1H-Pyrazolo[3,4-b]pyridin-3-amine, 4-methyl-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 4-Methyl-6-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-3-ylamine is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our products are developed to meet the exacting standards required for pharmaceutical R&D and advanced chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.