Description

4-(3,4-Dimethyl-Phenyl)-2-Mercapto-6-Trifluoromethyl-Nicotinonitrile is a high-value, multi-functional heterocyclic building block characterized by its trifluoromethyl and mercapto substituents. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in constructing advanced herbicides and fungicides, leveraging the trifluoromethyl group for enhanced efficacy.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in specialty polymer development.
• Chemical Biology: Employed as a probe or building block in the study of enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules on various scales.

Basic Information

Product Name	4-(3,4-Dimethyl-Phenyl)-2-Mercapto-6-Trifluoromethyl-Nicotinonitrile
CAS No.	832739-56-7
Molecular Formula	C15H11F3N2S
Molecular Weight	308.32 g/mol
Synonyms	2-Mercapto-4-(3,4-dimethylphenyl)-6-(trifluoromethyl)nicotinonitrile; 6-Trifluoromethyl-4-(3,4-dimethylphenyl)-2-mercaptonicotinonitrile; 4-(3,4-Dimethylphenyl)-2-mercapto-6-(trifluoromethyl)pyridine-3-carbonitrile; 832739-56-7; Nicotinonitrile, 4-(3,4-dimethylphenyl)-2-mercapto-6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 4-(3,4-Dimethyl-Phenyl)-2-Mercapto-6-Trifluoromethyl-Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.