Description

6-(Difluoromethyl)-4-(4-Methylphenyl)-2-Thioxo-1,2-Dihydropyridine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique dihydropyridine-thioxo core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic frameworks. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug molecules, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Serves as a core structure for developing new generations of herbicides and fungicides with specific modes of action.
• Chemical Synthesis Building Block: Used in organic synthesis to construct complex nitrogen and sulfur-containing heterocycles for material science and catalysis research.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	6-(Difluoromethyl)-4-(4-Methylphenyl)-2-Thioxo-1,2-Dihydropyridine-3-Carbonitrile
CAS No.	832737-93-6
Molecular Formula	C14H10F2N2S
Molecular Weight	276.31 g/mol
Synonyms	4-(p-Tolyl)-6-(difluoromethyl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile; 4-(4-Methylphenyl)-6-(difluoromethyl)-2-thioxo-1,2-dihydro-3-pyridinecarbonitrile; 6-(Difluoromethyl)-4-(4-methylphenyl)-2-thioxo-1,2-dihydro-3-pyridinecarbonitrile; 2-Thioxo-6-(difluoromethyl)-4-(4-methylphenyl)-1,2-dihydropyridine-3-carbonitrile; CAS 832737-93-6
EINECS	Contact for details

Quality Control

Our 6-(Difluoromethyl)-4-(4-Methylphenyl)-2-Thioxo-1,2-Dihydropyridine-3-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.