Description

1-[5-(Trifluoromethyl)Pyridin-2-Yl]Piperidin-4-Ol is a high-value trifluoromethylpyridine-piperidine hybrid compound, serving as a critical building block in modern synthetic chemistry. Its unique structure, combining a piperidine alcohol with a fluorinated pyridine ring, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of new molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and biological efficacy.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A pivotal starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-[5-(Trifluoromethyl)Pyridin-2-Yl]Piperidin-4-Ol
CAS No.	832715-03-4
Molecular Formula	C11H13F3N2O
Molecular Weight	246.23 g/mol
Synonyms	4-Piperidinol, 1-[5-(trifluoromethyl)-2-pyridinyl]-; 1-(5-(Trifluoromethyl)pyridin-2-yl)piperidin-4-ol; 2-(4-Hydroxypiperidin-1-yl)-5-(trifluoromethyl)pyridine; 4-Hydroxy-1-[5-(trifluoromethyl)-2-pyridyl]piperidine; 1-(5-Trifluoromethyl-2-pyridyl)-4-piperidinol
EINECS	Contact for details

Quality Control

Our 1-[5-(Trifluoromethyl)Pyridin-2-Yl]Piperidin-4-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.