Description

2,8-Diazaspiro[4.5]Decan-1-One, 2-[(4-Bromophenyl)Methyl]-, Hydrochloride (1:1) is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and diaza scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by pharmaceutical R&D laboratories, process development chemists, and fine chemical manufacturers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Employed in the multi-step synthesis of complex target molecules for preclinical and clinical studies.
• CNS Drug Development: Particularly relevant for constructing molecules targeting neurological disorders due to its structural features.
• Oncology Research: Serves as a building block for potential kinase inhibitors and other targeted cancer therapies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Used in university and institutional labs for chemical biology and novel synthetic methodology development.

Basic Information

Item	Details
Product Name	2,8-Diazaspiro[4.5]Decan-1-One, 2-[(4-Bromophenyl)Methyl]-, Hydrochloride (1:1)
CAS No.	832710-56-2
Molecular Formula	C15H20BrN2O • HCl
Molecular Weight	377.70 g/mol
Synonyms	2-[(4-Bromophenyl)methyl]-2,8-diazaspiro[4.5]decan-1-one hydrochloride; 2-(4-Bromobenzyl)-2,8-diazaspiro[4.5]decan-1-one hydrochloride; 1-Oxo-2,8-diazaspiro[4.5]decane-2-(4'-bromobenzyl) hydrochloride; 832710-56-2; UNII-8V8S5013QH; 8V8S5013QH; Spiro[4.5]decan-1-one, 2,8-diaza-2-[(4-bromophenyl)methyl]-, hydrochloride (1:1); AKOS025311193
EINECS	Contact for details

Quality Control

Every batch of 2,8-Diazaspiro[4.5]Decan-1-One, 2-[(4-Bromophenyl)Methyl]-, Hydrochloride (1:1) is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity suitable for research and development applications. Comprehensive Certificates of Analysis (COA) with full analytical data are provided with each shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.