Description

(Z)-tert-Butyl 2-(5-Bromopyridin-2(1H)-Ylidene)-2-Cyanoacetate is a high-value, light-sensitive chemical intermediate featuring a bromopyridine core and a cyanoacetate ester group. This compound matters for its role as a versatile building block in the synthesis of complex heterocyclic molecules, enabling the development of novel active ingredients. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its bromine atom for further functionalization.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials and specialty polymers.
• Chemical Synthesis: Acts as a versatile electrophile or Michael acceptor in organic synthesis for constructing complex pyridine-based heterocycles.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: Utilized in university and CRO laboratories for medicinal chemistry programs and methodological studies.

Basic Information

Product Name	(Z)-tert-Butyl 2-(5-Bromopyridin-2(1H)-Ylidene)-2-Cyanoacetate
CAS No.	831203-34-0
Molecular Formula	C12H13BrN2O2
Molecular Weight	297.15 g/mol
Synonyms	tert-Butyl (Z)-2-(5-bromo-2-oxo-1,2-dihydropyridin-1-ylidene)-2-cyanoacetate; 2-(5-Bromo-2-oxo-1,2-dihydropyridin-1-ylidene)-2-cyanoacetic acid tert-butyl ester; 5-Bromo-2-[(Z)-(2-tert-butoxy-1-cyano-2-oxoethylidene)amino]pyridine; 1H-Pyridin-2-one, 5-bromo-1-[(Z)-2-(1,1-dimethylethoxy)-1-cyano-2-oxoethylidene]-1,2-dihydro-; (Z)-2-(5-Bromo-2-oxo-1,2-dihydropyridin-1(2H)-ylidene)-2-cyanoacetic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (Z)-tert-Butyl 2-(5-Bromopyridin-2(1H)-Ylidene)-2-Cyanoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing HPLC purity, NMR confirmation, and residual solvent levels are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this moisture-sensitive material from humidity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.