Description

Methyl (2S)-2-Amino-3-(2,4-Dimethylphenyl)Propanoate CAS NO 831191-86-7 is a high-purity, non-natural amino acid ester derivative characterized by its chiral (S)-configuration and substituted phenyl ring. This compound is a critical chiral building block and intermediate in advanced organic synthesis, valued for its role in constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents and active pharmaceutical ingredients (APIs).
• Peptidomimetics & Drug Discovery: Used as a constrained amino acid analog for designing and synthesizing peptide-based drugs and enzyme inhibitors with enhanced metabolic stability.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective chemical reactions to introduce the (S)-amino acid configuration.
• Agrochemical Research: Employed in the development of novel, biologically active compounds for crop protection and agricultural science.
• Material Science: Investigated as a monomer or precursor for specialized polymers and functional materials with unique properties.
• Academic & Contract Research: Essential for fundamental chemical research and custom synthesis projects in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	Methyl (2S)-2-Amino-3-(2,4-Dimethylphenyl)Propanoate
CAS No.	831191-86-7
Molecular Formula	C₁₂H₁₇NO₂
Molecular Weight	207.27 g/mol
Synonyms	Methyl L-2-Amino-3-(2,4-dimethylphenyl)propanoate; (S)-Methyl 2-amino-3-(2,4-dimethylphenyl)propanoate; Methyl (S)-2-Amino-3-(2,4-dimethylphenyl)propionate; L-2,4-Dimethylphenylalanine methyl ester; 2,4-Dimethyl-DL-phenylalanine methyl ester (related); 831191-86-7; Amino acid ester derivative
EINECS	Contact for details

Quality Control

Our production of Methyl (2S)-2-Amino-3-(2,4-Dimethylphenyl)Propanoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is subjected to comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR spectroscopy, and quantification of key impurities. Certificates of Analysis (COA) documenting all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (S-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.