Description

2-{[1-(3-Nitrophenyl)-2,5-Dioxopyrrolidin-3-Yl]Sulfanyl}Pyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular architecture combining pyrrolidine and pyridine moieties. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex disease pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, where its specific structure enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of novel drug candidates, especially in oncology and neurology.
• Chemical Research & Development: Used as a specialized reagent in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• API Synthesis: Employed in the multi-step synthesis of complex target molecules for pre-clinical and clinical trials.
• Bioconjugation Chemistry: Potential use in developing antibody-drug conjugates (ADCs) or other targeted therapies due to its reactive functional groups.
• Academic Research: Utilized in university and institutional labs for investigating new chemical reactions and heterocyclic compound properties.

Basic Information

Product Name	2-{[1-(3-Nitrophenyl)-2,5-Dioxopyrrolidin-3-Yl]Sulfanyl}Pyridine-3-Carboxylic Acid
CAS No.	830348-50-0
Molecular Formula	C16H11N3O5S
Molecular Weight	357.34 g/mol
Synonyms	2-({1-[3-Nitrophenyl]-2,5-dioxo-3-pyrrolidinyl}sulfanyl)-3-pyridinecarboxylic acid; 2-{[1-(3-Nitrophenyl)-2,5-dioxopyrrolidin-3-yl]thio}nicotinic acid; 3-Pyridinecarboxylic acid, 2-[[1-(3-nitrophenyl)-2,5-dioxo-3-pyrrolidinyl]thio]-; 830348-50-0; 2-((1-(3-Nitrophenyl)-2,5-dioxopyrrolidin-3-yl)thio)nicotinic acid
EINECS	Contact for details

Quality Control

Our production of 2-{[1-(3-Nitrophenyl)-2,5-Dioxopyrrolidin-3-Yl]Sulfanyl}Pyridine-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive pharmaceutical R&D. All materials undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light) and should be handled with appropriate precautions for strong acid/organic solvent compatibility. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.