Description

1H-Pyrrolizine, Hexahydro-3-Methyl-5-(Phenylmethyl)-, (3R,5R,7As)-Rel- is a high-purity, stereochemically defined pyrrolizine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile chiral intermediate, enabling the construction of complex molecular architectures with precise stereochemical control. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly those developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for research and industrial applications.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in stereoselective synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	1H-Pyrrolizine, Hexahydro-3-Methyl-5-(Phenylmethyl)-, (3R,5R,7As)-Rel-
CAS No.	830335-30-3
Molecular Formula	C15H21N
Molecular Weight	215.33 g/mol
Synonyms	rel-(3R,5R,7aR)-Hexahydro-3-methyl-5-(phenylmethyl)-1H-pyrrolizine; 1H-Pyrrolizine, hexahydro-3-methyl-5-(phenylmethyl)-, (3R,5R,7aR)-rel-; 830335-30-3; 3-Methyl-5-benzylhexahydro-1H-pyrrolizine (relative stereochemistry); Chiral 3-methyl-5-benzylpyrrolizidine; Pyrrolizidine derivative intermediate; CAS 830335-30-3
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our production adheres to cGMP guidelines where applicable, and each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. Standard analytical techniques including HPLC, GC, and NMR are employed to verify identity and meet customer-specific specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.