Description

Methyl (2S,3E)-2-Hydroxy-4-(4-Methylphenyl)-3-Butenoate is a high-purity chiral building block characterized by its specific stereochemistry and functional groups. This compound is valued for its role as a key synthetic intermediate in the production of complex organic molecules, where precise stereocontrol is critical. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and drug discovery.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in routes requiring stereoselective synthesis.
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for generating compound libraries in the search for new therapeutic agents.
• Fine Chemical Production: Employed in the synthesis of specialty chemicals, flavors, fragrances, and advanced materials where specific stereochemistry is required.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	Methyl (2S,3E)-2-Hydroxy-4-(4-Methylphenyl)-3-Butenoate
CAS No.	830319-51-2
Molecular Formula	C12H14O3
Molecular Weight	206.24 g/mol
Synonyms	(2S,3E)-2-Hydroxy-4-(p-tolyl)but-3-enoic acid methyl ester; Methyl (2S,3E)-2-hydroxy-4-(p-tolyl)-3-butenoate; (S,E)-Methyl 2-hydroxy-4-(4-methylphenyl)but-3-enoate; (2S,3E)-Methyl 2-hydroxy-4-(4-methylphenyl)-3-butenoate; p-Methylcinnamyl alcohol derivative, methyl ester; Chiral hydroxy butenoate ester
EINECS	Contact for details

Quality Control

Our production of Methyl (2S,3E)-2-Hydroxy-4-(4-Methylphenyl)-3-Butenoate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and stereochemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.