Description

1-Piperidinecarboxylic Acid, 3-Hydroxy-2-Methoxy-, Methyl Ester is a specialized piperidine derivative, a high-purity synthetic intermediate of significant value in advanced organic synthesis. Its unique structure, featuring both hydroxy and methoxy substituents, makes it a versatile building block for constructing complex molecules with precise stereochemistry. This compound is primarily sought after by research institutions and pharmaceutical development teams for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its piperidine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic and Industrial Research: Employed in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex natural product analogs and specialty performance chemicals.

Basic Information

Product Name	1-Piperidinecarboxylic Acid, 3-Hydroxy-2-Methoxy-, Methyl Ester
CAS No.	828699-57-6
Molecular Formula	C9H17NO4
Molecular Weight	203.24 g/mol
Synonyms	Methyl 3-hydroxy-2-methoxypiperidine-1-carboxylate; 3-Hydroxy-2-methoxy-1-piperidinecarboxylic acid methyl ester; 1-Carbomethoxy-3-hydroxy-2-methoxypiperidine; 2-Methoxy-3-hydroxypiperidine-1-carboxylic acid methyl ester; (3-Hydroxy-2-methoxypiperidin-1-yl)methanone, methyl ester; Piperidine-1-carboxylic acid, 3-hydroxy-2-methoxy-, methyl ester
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxylic Acid, 3-Hydroxy-2-Methoxy-, Methyl Ester is manufactured under strict quality management systems. We provide material with typical purities exceeding 97% (by HPLC), tailored to meet the stringent requirements of research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with every batch to ensure full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.