Description

1-Piperidinecarboxylicacid,3-Cyano-2-Methyl-,1,1-Dimethylethylester,(2R,3R)-Rel-(9Ci) is a high-purity, stereochemically defined piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its unique molecular architecture, which provides a versatile scaffold for constructing complex, biologically active molecules with precise stereocontrol. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, especially for central nervous system (CNS) targets and enzyme inhibitors.
• Agrochemical Research: Used as a building block for developing novel pesticides and herbicides with specific stereochemical requirements for enhanced activity.
• Asymmetric Catalysis: Employed as a precursor or ligand in the development of chiral catalysts for stereoselective reactions.
• Medicinal Chemistry: Serves as a core structure for structure-activity relationship (SAR) studies and the exploration of new chemical entities in drug discovery programs.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex, high-value specialty chemicals and advanced materials.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting research in synthetic organic chemistry and methodology development.

Basic Information

Product Name	1-Piperidinecarboxylicacid,3-Cyano-2-Methyl-,1,1-Dimethylethylester,(2R,3R)-Rel-(9Ci)
CAS No.	828300-48-7
Molecular Formula	C13H22N2O2
Molecular Weight	238.33 g/mol
Synonyms	(2R,3R)-rel-3-Cyano-2-methyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl (2R,3R)-rel-3-cyano-2-methylpiperidine-1-carboxylate; (rel)-(2R,3R)-1-Boc-3-cyano-2-methylpiperidine; 1-Boc-3-cyano-2-methylpiperidine (rel-(2R,3R)-); 1-(tert-Butoxycarbonyl)-3-cyano-2-methylpiperidine (rel-(2R,3R)-); (2R*,3R*)-tert-Butyl 3-cyano-2-methylpiperidine-1-carboxylate; 828300-48-7; (R*,R*)-tert-Butyl 3-cyano-2-methylpiperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our production of 1-Piperidinecarboxylicacid,3-Cyano-2-Methyl-,1,1-Dimethylethylester,(2R,3R)-Rel-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to meet the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.