Description

(3Ar,4R,7As)-3A,4,5,7A-Tetrahydro-4-Methylspiro[1,3-Benzodioxole-2,1′-Cyclohexane] is a high-purity, specialized spirocyclic compound with the CAS registry number 828268-88-8. This structurally unique molecule serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis. It is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require precise stereochemistry and complex molecular architecture for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Asymmetric Catalysis: Serves as a ligand or a core structure for designing novel chiral catalysts.
• Material Science Research: Investigated as a monomer or additive for creating polymers with unique thermal or mechanical properties.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex odorants and flavor compounds.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry, including novel cyclization and spiroannulation reactions.

Basic Information

Product Name	(3Ar,4R,7As)-3A,4,5,7A-Tetrahydro-4-Methylspiro[1,3-Benzodioxole-2,1′-Cyclohexane]
CAS No.	828268-88-8
Molecular Formula	C14H22O2
Molecular Weight	222.32 g/mol
Synonyms	4-Methylspiro[1,3-benzodioxole-2,1'-cyclohexane]; 4-Methyl-2,3,4,7-tetrahydrospiro[[1,3]dioxolo[4,5-f]indole-8,1'-cyclohexane] (non-IUPAC); (3aR,4R,7aS)-4-Methylhexahydrospiro[[1,3]dioxolo[4,5-f]indole-8,1'-cyclohexane]; Spirocyclic benzodioxole derivative; CAS 828268-88-8; Tetrahydro-methyl-spiro-benzodioxole-cyclohexane
EINECS	Contact for details

Quality Control

Every batch of (3Ar,4R,7As)-3A,4,5,7A-Tetrahydro-4-Methylspiro[1,3-Benzodioxole-2,1′-Cyclohexane] is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements of R&D and scale-up processes. A Certificate of Analysis (COA) detailing chiral purity, assay, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.