Description

3H-Imidazo[4,5-B]Pyridine-2-Methanamine is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is primarily sought after by research institutions and pharmaceutical companies developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: Serves as a privileged structure in the design and synthesis of potential kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Synthesis: Employed in the research and development of novel crop protection agents and pesticides.
• Material Science Research: Investigated as a building block for organic electronic materials and ligands in catalytic systems.

Basic Information

Item	Details
Product Name	3H-Imidazo[4,5-B]Pyridine-2-Methanamine
CAS No.	828242-03-1
Molecular Formula	C7H8N4
Molecular Weight	148.16 g/mol
Synonyms	2-(Aminomethyl)-3H-imidazo[4,5-b]pyridine; 3H-Imidazo[4,5-b]pyridine-2-methanamine; 2-(Aminomethyl)imidazo[4,5-b]pyridine; 2-(Aminomethyl)-1H-imidazo[4,5-b]pyridine; 828242-03-1; Imidazo[4,5-b]pyridine-2-methanamine; SCHEMBL18883027
EINECS	Contact for details

Quality Control

Our production of 3H-Imidazo[4,5-B]Pyridine-2-Methanamine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.