Description

(1-(5-Bromopyridin-2-Yl)Cyclopropyl)Methanol is a high-purity, advanced pharmaceutical intermediate featuring a unique bromopyridine-cyclopropylmethanol scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Building Block: Used in structure-activity relationship (SAR) studies and lead optimization due to its functionalized pyridine and strained cyclopropane rings.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and insecticides that require halogenated heterocyclic components.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.
• Academic & Institutional Research: Used in university and institutional laboratories for fundamental research in organic synthesis and new reaction methodology development.

Basic Information

Item	Detail
Product Name	(1-(5-Bromopyridin-2-Yl)Cyclopropyl)Methanol
CAS No.	827628-20-6
Molecular Formula	C9H10BrNO
Molecular Weight	228.09 g/mol
Synonyms	(1-(5-Bromopyridin-2-yl)cyclopropyl)methanol; 2-(1-(Hydroxymethyl)cyclopropyl)-5-bromopyridine; 5-Bromo-2-(1-(hydroxymethyl)cyclopropyl)pyridine; (1-(5-Bromo-2-pyridinyl)cyclopropyl)methanol; 827628-20-6; (1-(5-Bromopyridin-2-yl)cyclopropyl)methanol
EINECS	Contact for details

Quality Control

Our (1-(5-Bromopyridin-2-Yl)Cyclopropyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere or inert gas to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.