Description

1-(6-Bromopyridin-3-Yl)Cyclopropanecarbonitrile is a high-value brominated pyridine derivative and versatile chemical building block. Its molecular architecture, featuring both a bromine substituent and a nitrile-functionalized cyclopropane ring, makes it a critical intermediate for constructing complex molecules in advanced research and development. This compound is primarily sought by pharmaceutical and agrochemical R&D teams for the synthesis of novel active ingredients, including potential kinase inhibitors and other biologically relevant heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in the synthesis of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging its halogen and nitrile functionality for structural diversification.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, organic semiconductors, and other functional materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.
• Academic & Industrial R&D: Utilized in exploratory chemistry for method development and the creation of novel chemical libraries.

Basic Information

Product Name	1-(6-Bromopyridin-3-Yl)Cyclopropanecarbonitrile
CAS No.	827628-16-0
Molecular Formula	C9H7BrN2
Molecular Weight	223.07 g/mol
Synonyms	1-(6-Bromo-3-pyridinyl)cyclopropanecarbonitrile; Cyclopropanecarbonitrile, 1-(6-bromo-3-pyridinyl)-; 1-(6-Bromopyridin-3-yl)cyclopropane-1-carbonitrile; 3-(1-Cyanocyclopropyl)-6-bromopyridine; 6-Bromo-3-(1-cyanocyclopropyl)pyridine; 827628-16-0
EINECS	Contact for details

Quality Control

Our 1-(6-Bromopyridin-3-Yl)Cyclopropanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable material for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.