Description

Ethyl (4R,5S)-5-Butyl-2,2-Dimethyl-1,3-Dioxolane-4-Carboxylate is a high-value chiral building block and intermediate, prized for its defined stereochemistry and functional group versatility. This compound is critical for synthesizing complex molecules where precise spatial orientation is required for biological activity or material properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, antifungal, or cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where stereochemistry influences efficacy and environmental profile.
• Flavor & Fragrance Chemistry: Serves as a precursor for synthesizing specific, high-value aroma compounds and flavoring agents.
• Ligand & Catalyst Development: Employed in organic and organometallic chemistry to create novel chiral ligands and catalysts for asymmetric transformations.
• Material Science Research: Acts as a monomer or modifying agent in the development of specialized polymers with tailored optical or mechanical properties.
• Academic & Process Chemistry: A valuable reagent for methodological studies in synthetic organic chemistry and for scaling up novel synthetic routes.

Basic Information

Product Name	Ethyl (4R,5S)-5-Butyl-2,2-Dimethyl-1,3-Dioxolane-4-Carboxylate
CAS No.	827623-54-1
Molecular Formula	C12H22O4
Molecular Weight	230.30 g/mol
Synonyms	(4R,5S)-Ethyl 5-Butyl-2,2-dimethyl-1,3-dioxolane-4-carboxylate; Ethyl (4R-cis)-5-Butyl-2,2-dimethyl-1,3-dioxolane-4-carboxylate; (4R,5S)-5-Butyl-2,2-dimethyl-1,3-dioxolane-4-carboxylic Acid Ethyl Ester; (4R,5S)-5-n-Butyl-2,2-dimethyl-1,3-dioxolane-4-carboxylic Acid Ethyl Ester; 827623-54-1; Butyl Dioxolane Carboxylate Ethyl Ester; Chiral Butyl Dioxolane Ester
EINECS	Contact for details

Quality Control

Our Ethyl (4R,5S)-5-Butyl-2,2-Dimethyl-1,3-Dioxolane-4-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.