Description

4-Pyridinecarbonitrile,3,5-Bis(Trimethylsilyl)-(9Ci) is a specialized organosilicon-protected pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic silyl protection of the pyridine ring, which enhances stability and directs regioselectivity in complex coupling and functionalization reactions. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for targeted therapies and complex heterocyclic active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the pyridine core is a common bioactive motif.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in transition metal catalysis for fine chemical production.
• Materials Science Research: Building block for organic electronic materials, such as components for OLEDs or conductive polymers, due to its tunable electronic properties.
• Chemical Synthesis: Employed in academic and industrial R&D for method development and the construction of complex, polyfunctionalized pyridine systems.

Basic Information

Item	Detail
Product Name	4-Pyridinecarbonitrile,3,5-Bis(Trimethylsilyl)-(9Ci)
CAS No.	827616-49-9
Molecular Formula	C14H24N2Si2
Molecular Weight	276.53 g/mol
Synonyms	3,5-Bis(trimethylsilyl)isonicotinonitrile; 3,5-Bis(trimethylsilyl)-4-cyanopyridine; 4-Cyano-3,5-bis(trimethylsilyl)pyridine; Isonicotinonitrile, 3,5-bis(trimethylsilyl)-; 4-Pyridinecarbonitrile, 3,5-bis(trimethylsilyl)-
EINECS	Contact for details

Quality Control

Our production of 4-Pyridinecarbonitrile,3,5-Bis(Trimethylsilyl)-(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.