Description

(2-Hydroxymethyl-Pyridin-3-Yl)-Carbamic Acid tert-Butyl Ester CAS NO 824429-51-8 is a high-purity, protected intermediate of significant value in advanced organic synthesis. Its core value proposition lies in providing a versatile and reactive pyridine-based building block with orthogonal protecting groups, enabling the efficient construction of complex molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting the central nervous system or as kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require functionalized pyridine scaffolds.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Research: The hydroxymethyl and protected carbamate functionalities make it valuable for constructing non-natural amino acid analogs and peptide-like structures.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise, multi-step functionalization on a pyridine core.

Basic Information

Product Name	(2-Hydroxymethyl-Pyridin-3-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	824429-51-8
Molecular Formula	C12H18N2O3
Molecular Weight	238.28 g/mol
Synonyms	tert-Butyl N-(2-hydroxymethyl-3-pyridinyl)carbamate; 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-pyridinemethanol; 2-(Hydroxymethyl)-N-Boc-3-aminopyridine; N-Boc-3-amino-2-pyridinemethanol; Boc-3-Amino-2-pyridinemethanol; 3-(N-Boc-amino)-2-(hydroxymethyl)pyridine; (3-Amino-2-pyridyl)methanol N-Boc derivative
EINECS	Contact for details

Quality Control

Our (2-Hydroxymethyl-Pyridin-3-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.