Description

Pyridine, 5-Chloro-4-Iodo-2-(Trifluoromethyl)- is a highly functionalized pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique halogenated and trifluoromethylated structure makes it an indispensable building block for constructing complex molecules with tailored properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by material scientists exploring specialty polymers and electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging its halogen and fluorine motifs for bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands in catalysis and as a monomer or additive in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes, tags, and linkers used in bioconjugation and target identification studies.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Pyridine, 5-Chloro-4-Iodo-2-(Trifluoromethyl)-
CAS No.	823221-95-0
Molecular Formula	C7H2ClF3IN
Molecular Weight	337.45 g/mol
Synonyms	5-Chloro-4-iodo-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-5-chloro-4-iodopyridine; 5-Chloro-4-iodo-2-trifluoromethylpyridine; 4-Iodo-5-chloro-2-(trifluoromethyl)pyridine; Pyridine, 5-chloro-4-iodo-2-(trifluoromethyl)-; 823221-95-0; 5-Chloro-4-iodo-2-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our production of Pyridine, 5-Chloro-4-Iodo-2-(Trifluoromethyl)- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP (current Good Manufacturing Practice) standards for applications requiring the highest level of quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Due to its sensitivity as a fluoride/strong alkali compound, keep away from incompatible materials such as strong acids and oxidizing agents. Ensure the container is kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.