Description

5-Fluoro-3-Iodo-Pyridin-2-Ylamine is a halogenated pyridine derivative serving as a versatile and high-value building block in advanced organic synthesis. Its molecular structure, featuring both fluorine and iodine substituents on the pyridine core, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides due to its bioactive scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and diagnostic assay development.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	5-Fluoro-3-Iodo-Pyridin-2-Ylamine
CAS No.	823218-51-5
Molecular Formula	C5H4FIN2
Molecular Weight	237.99 g/mol
Synonyms	2-Amino-5-fluoro-3-iodopyridine; 3-Iodo-5-fluoropyridin-2-amine; 5-Fluoro-3-iodopyridin-2-amine; 2-Pyridinamine, 5-fluoro-3-iodo-; 5-Fluoro-3-iodo-2-aminopyridine; 5-Fluoro-3-iodo-2-pyridinamine; 823218-51-5; 5-Fluoro-3-iodopyridin-2-ylamine
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-3-Iodo-Pyridin-2-Ylamine is manufactured and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our standard quality control includes comprehensive analysis via HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.