Description

(E)-Methyl 3-(2-Amino-5-Methylpyridin-3-Yl)-Acrylate is a high-purity, functionalized acrylate ester derivative featuring an amino-pyridine moiety, making it a versatile and valuable building block in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals due to its reactive double bond and heterocyclic amine group. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating complex chelating ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic materials due to its polymerizable acrylate group.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, high-value heterocyclic compounds.

Basic Information

Product Name	(E)-Methyl 3-(2-Amino-5-Methylpyridin-3-Yl)-Acrylate
CAS No.	823218-50-4
Molecular Formula	C10H12N2O2
Molecular Weight	192.22 g/mol
Synonyms	Methyl (2E)-3-(2-Amino-5-methyl-3-pyridinyl)-2-propenoate; (E)-Methyl 3-(2-Amino-5-methyl-3-pyridinyl)acrylate; 2-Propenoic acid, 3-(2-amino-5-methyl-3-pyridinyl)-, methyl ester, (2E)-; Methyl 3-(2-Amino-5-methylpyridin-3-yl)acrylate; 3-(2-Amino-5-methylpyridin-3-yl)acrylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of (E)-Methyl 3-(2-Amino-5-Methylpyridin-3-Yl)-Acrylate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming specifications for identity, purity (typically ≥97% by HPLC), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.