Description

Pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine, 5,5a,6,7,8,9-hexahydro-3,9-dimethyl-, (5aR,9R)- is a complex, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. This molecule matters as a sophisticated chemical building block for the development of novel pharmacologically active agents. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams focused on creating new molecular entities with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A key chiral scaffold in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or oncology targets.
• Medicinal Chemistry Research: Serves as a core structure for constructing compound libraries in drug discovery programs aimed at structure-activity relationship (SAR) studies.
• Advanced Organic Synthesis: Used as a specialized precursor for the synthesis of complex, polycyclic nitrogen-containing heterocycles.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes to study biological pathways and protein functions.
• Asymmetric Synthesis: Utilized in reactions requiring high stereoselectivity due to its defined chiral centers at positions 5aR and 9R.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis services for the life sciences industry.

Basic Information

Product Name	Pyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine, 5,5a,6,7,8,9-hexahydro-3,9-dimethyl-, (5aR,9R)-
CAS No.	823217-40-9
Molecular Formula	C13H17N3
Molecular Weight	215.30 g/mol
Synonyms	(5aR,9R)-5,5a,6,7,8,9-Hexahydro-3,9-dimethylpyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine; (5aR,9R)-3,9-Dimethyl-5,5a,6,7,8,9-hexahydropyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine; Hexahydro-3,9-dimethylpyrido[3',2':4,5]pyrrolo[1,2-a]pyrazine (5aR,9R)-; A complex fused tetracyclic amine; A chiral pyrrolopyrazine derivative.
EINECS	Contact for details

Quality Control

Our high-value chemical building blocks are produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and spectroscopic identification (NMR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the results against agreed specifications to ensure consistency and reliability for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.