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6-tert-Butyl 3-Ethyl 4,5-Dihydro-2H-Pyrazolo[3,4-C]Pyridine-3,6(7H)-Dicarboxylate CAS NO 821785-75-5


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CAS No.:821785-75-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-tert-Butyl 3-Ethyl 4,5-Dihydro-2H-Pyrazolo[3,4-C]Pyridine-3,6(7H)-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyridine class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

  • Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of novel drug candidates, especially those targeting kinase inhibition.
  • Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop compounds with improved efficacy and pharmacokinetic profiles.
  • Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
  • Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
  • Biochemical Tool Compound: May be used as a scaffold or reference standard in biochemical assays and high-throughput screening (HTS) campaigns.

Basic Information

Product Name 6-tert-Butyl 3-Ethyl 4,5-Dihydro-2H-Pyrazolo[3,4-C]Pyridine-3,6(7H)-Dicarboxylate
CAS No. 821785-75-5
Molecular Formula C16H25N3O4
Molecular Weight 323.39 g/mol
Synonyms tert-Butyl 3-ethyl 4,7-dihydro-2H-pyrazolo[3,4-c]pyridine-3,6(5H)-dicarboxylate; 3-Ethyl 6-tert-butyl 4,5-dihydro-2H,7H-pyrazolo[3,4-c]pyridine-3,6-dicarboxylate; 6-(tert-Butyl) 3-ethyl 4,7-dihydro-2H-pyrazolo[3,4-c]pyridine-3,6(5H)-dicarboxylate; 3-Ethyl 6-tert-butyl 4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine-3,6-dicarboxylate; 821785-75-5; Pyrazolopyridine dicarboxylate intermediate
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Quality Control

Our 6-tert-Butyl 3-Ethyl 4,5-Dihydro-2H-Pyrazolo[3,4-C]Pyridine-3,6(7H)-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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