Description

3,3'-(2,5-Pyridinediyl)Bis-2-Propyn-1-Ol is a specialized organic compound featuring a central pyridine ring symmetrically substituted with propargyl alcohol groups. This unique bifunctional structure, containing both a heterocyclic aromatic system and terminal alkyne moieties, makes it a valuable high-purity building block for advanced chemical synthesis. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors, where it serves as a key precursor for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other heterocyclic-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, leveraging its pyridine core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis due to its alkyne functional groups.
• Material Science Research: Employed in the synthesis of novel polymers, dendrimers, and metal-organic frameworks (MOFs) where its rigid, symmetrical structure is advantageous.
• Chemical Biology Probe: Utilized in bioconjugation and click chemistry applications to label or modify biomolecules, proteins, and peptides.
• Fine Chemical Production: Acts as a building block for the manufacture of other complex, high-value specialty chemicals.

Basic Information

Product Name	3,3'-(2,5-Pyridinediyl)Bis-2-Propyn-1-Ol
CAS No.	820965-58-0
Molecular Formula	C11H7NO2
Molecular Weight	185.18 g/mol
Synonyms	2,5-Bis(3-hydroxyprop-1-yn-1-yl)pyridine; 2,5-Di(2-propyn-1-ol)pyridine; 2,5-Bis(2-propynyloxy)pyridine (common misnomer); 2,5-Bis(prop-2-yn-1-yloxy)pyridine; 2,5-Dipropargyloxypyridine; 1,1'-(Pyridine-2,5-diyl)bis(prop-2-yn-1-ol); 3,3'-(Pyridine-2,5-diyl)diprop-2-yn-1-ol
EINECS	Contact for details

Quality Control

Our 3,3'-(2,5-Pyridinediyl)Bis-2-Propyn-1-Ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and scale-up applications. Comprehensive Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.