Description

R-Cyclopentylglycine Methyl Ester is a high-purity chiral building block and protected amino acid derivative essential for advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide mimetics, drug discovery, and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptidomimetics Synthesis: Used to introduce the constrained cyclopentylglycine moiety into peptide backbones to enhance metabolic stability and binding affinity.
• Asymmetric Synthesis: Serves as a versatile building block in stereoselective reactions for constructing complex natural products and fine chemicals.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides that require specific chiral configurations for activity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity chiral intermediates.

Basic Information

Product Name	R-Cyclopentylglycine Methyl Ester
CAS No.	820964-60-1
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(R)-2-Amino-2-cyclopentylacetic acid methyl ester; Methyl (R)-2-amino-2-cyclopentylacetate; (R)-Cyclopentylglycine methyl ester; (R)-Aminocyclopentaneacetic acid methyl ester; (R)-Methyl 2-amino-2-cyclopentylacetate; (R)-α-Aminocyclopentanecetic acid methyl ester; (2R)-2-Amino-2-cyclopentylacetic acid methyl ester
EINECS	Contact for details

Quality Control

Our R-Cyclopentylglycine Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to verify identity, enantiomeric excess, and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and our quality system supports cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.