Description

(5-Chlorosulfonyl-Naphthalen-1-Yl)-Carbamic Acid Pyridin-3-Ylmethyl Ester is a specialized organic intermediate featuring a reactive chlorosulfonyl group and a carbamate ester linkage. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries seeking to incorporate naphthalene and pyridine motifs into target structures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting neurological or oncological pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, where the naphthalene sulfonyl chloride derivative acts as a reactive handle.
• Material Science Chemistry: Employed in the creation of specialty polymers, dyes, or photoactive materials that require specific aromatic sulfonamide functionalities.
• Bioconjugation & Probe Synthesis: The reactive chlorosulfonyl group enables its use in modifying biomolecules or creating fluorescent or affinity probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	(5-Chlorosulfonyl-Naphthalen-1-Yl)-Carbamic Acid Pyridin-3-Ylmethyl Ester
CAS No.	820245-87-2
Molecular Formula	C₁₇H₁₃ClN₂O₄S
Molecular Weight	376.81 g/mol
Synonyms	5-(Chlorosulfonyl)-1-naphthyl carbamic acid 3-pyridylmethyl ester; 3-Pyridinemethanol, 5-(chlorosulfonyl)-1-naphthalenylcarbamate; 1-Naphthalenylcarbamic acid 5-(chlorosulfonyl)-, 3-pyridinylmethyl ester; Pyridin-3-ylmethyl (5-chlorosulfonylnaphthalen-1-yl)carbamate; (5-Chlorosulfonyl-1-naphthyl)carbamic acid pyridin-3-ylmethyl ester
EINECS	Contact for details

Quality Control

Our (5-Chlorosulfonyl-Naphthalen-1-Yl)-Carbamic Acid Pyridin-3-Ylmethyl Ester is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), physical characteristics, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.