Description

6-Chloro-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Hydrobromide is a high-purity organic salt building block of significant importance in advanced pharmaceutical research and development. Its core value lies in serving as a critical synthetic intermediate for the creation of novel drug candidates, particularly in therapeutic areas targeting the central nervous system and inflammatory diseases. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries who require reliable, high-quality chemical intermediates to accelerate their discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) with potential biological activity.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable manufacturing of target drug molecules.
• Bioconjugation & Probe Synthesis: The carboxylic acid functionality allows for derivatization, making it useful for creating biochemical probes and labeled compounds.
• Academic & Contract Research: Serves as a specialized reagent in university laboratories and CROs (Contract Research Organizations) focused on heterocyclic chemistry and drug discovery.

Basic Information

Product Name	6-Chloro-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Hydrobromide
CAS No.	820245-56-5
Molecular Formula	C8H6BrClN2O2
Molecular Weight	277.50 g/mol
Synonyms	6-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid hydrobromide; 6-Chloro-2-carboxyimidazo[1,2-a]pyridine hydrobromide; Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-chloro-, hydrobromide; 820245-56-5; 6-Chloroimidazo[1,2-a]pyridine-2-carboxylic acid HBr salt
EINECS	Contact for details

Quality Control

Our 6-Chloro-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Hydrobromide is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.