Description

Methyl 2-Bromo-6-Fluorobenzoate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its unique halogenated structure makes it a critical intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging the fluorine and bromine substituents for enhanced bioactivity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Organic Electronic Materials: Intermediate in the production of specialty polymers and small molecules for organic light-emitting diodes (OLEDs) and semiconductors.
• Cross-Coupling Reactions: Utilized in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to introduce the 2-bromo-6-fluorobenzoate moiety into complex architectures.
• Chemical Research & Development: A versatile reagent for academic and industrial research exploring new fluorinated heterocycles and functional materials.

Basic Information

Product Name	Methyl 2-Bromo-6-Fluorobenzoate
CAS No.	820236-81-5
Molecular Formula	C8H6BrFO2
Molecular Weight	233.04 g/mol
Synonyms	2-Bromo-6-fluorobenzoic acid methyl ester; Methyl 2-bromo-6-fluorobenzoate; Benzoic acid, 2-bromo-6-fluoro-, methyl ester; 6-Fluoro-2-bromobenzoic acid methyl ester; Methyl o-bromo-m-fluorobenzoate; 2-Bromo-6-fluorobenzoic acid, methyl ester; Methyl α-bromo-γ-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-6-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (GC)	≥96.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.