Description

Pyridine, 3-Ethynyl-5-[[(2S)-1-Methyl-2-Pyrrolidinyl]Methoxy]- (9Ci) is a sophisticated pyridine derivative featuring an ethynyl substituent and a chiral pyrrolidinylmethoxy side chain, making it a valuable building block in advanced organic synthesis. This compound is critical for research and development in medicinal chemistry, where its unique structure enables the creation of novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents and high-value intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand Synthesis: Employed in the development of novel ligands for catalysis or receptor binding studies due to its nitrogen-containing heterocycle and alkyne functionality.
• Fine Chemical Production: Acts as a specialized intermediate for manufacturing complex, high-purity organic compounds for research and development.
• Bioconjugation Chemistry: The ethynyl group can be utilized in click chemistry reactions (e.g., CuAAC) for labeling or conjugating biomolecules.

Basic Information

Product Name	Pyridine, 3-Ethynyl-5-[[(2S)-1-Methyl-2-Pyrrolidinyl]Methoxy]- (9Ci)
CAS No.	820231-75-2
Molecular Formula	C13H16N2O
Molecular Weight	216.28 g/mol
Synonyms	3-Ethynyl-5-[(2S)-1-methylpyrrolidin-2-yl]methoxypyridine; (S)-3-Ethynyl-5-((1-methylpyrrolidin-2-yl)methoxy)pyridine; 3-Ethynyl-5-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyridine; UNII-9F2R7S8A4T; 9F2R7S8A4T; SCHEMBL23346819; DTXSID90648669
EINECS	Contact for details

Quality Control

Every batch of Pyridine, 3-Ethynyl-5-[[(2S)-1-Methyl-2-Pyrrolidinyl]Methoxy]- (9Ci) is produced under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for chiral purity, chemical purity, and related substances analysis.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.