Description

Spiro[3.4]Octan-5-Ol, 5,6-Dimethyl-, (5R,6S)-Rel- (9Ci) is a chiral spirocyclic alcohol building block of significant interest in advanced organic synthesis. This compound matters for its defined stereochemistry and rigid molecular framework, which are critical for constructing complex molecules with precise three-dimensional architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in transition metal catalysis.
• Agrochemical Research: Used in the discovery and synthesis of new generation herbicides and pesticides with enhanced stereoselective activity.
• Material Science: Exploration as a monomer or additive for creating polymers with unique thermal and mechanical properties due to its spirocyclic structure.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including novel cyclization and ring-expansion reactions.
• Flavor & Fragrance Chemistry: Potential use in the synthesis of complex, stereochemically defined odorants and flavoring agents.

Basic Information

Product Name	Spiro[3.4]Octan-5-Ol, 5,6-Dimethyl-, (5R,6S)-Rel- (9Ci)
CAS No.	820222-81-9
Molecular Formula	C10H18O
Molecular Weight	154.25 g/mol
Synonyms	rel-(5R,6S)-5,6-Dimethylspiro[3.4]octan-5-ol; (5R,6S)-5,6-Dimethylspiro[3.4]octan-5-ol; 5,6-Dimethylspiro[3.4]octan-5-ol; Spiro[3.4]octan-5-ol, 5,6-dimethyl-, (5R,6S)-rel-; 820222-81-9; (5R,6S)-rel-5,6-Dimethylspiro[3.4]octan-5-ol
EINECS	Contact for details

Quality Control

Our Spiro[3.4]Octan-5-Ol, 5,6-Dimethyl-, (5R,6S)-Rel- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.