Description

Spiro[3.4]Octan-5-Ol, 6,6-Dimethyl- (9Ci) is a specialized spirocyclic alcohol building block of significant interest in advanced organic synthesis. Its unique bridged-ring structure provides a rigid, three-dimensional framework that is highly valuable for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor or scaffold in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, where its spiro structure can contribute to unique biological activity and stability.
• Ligand and Catalyst Development: Employed as a backbone for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with specific thermal or mechanical properties.
• Fragrance and Flavor Chemistry: Investigated for its potential as a building block for novel synthetic musk compounds or other complex odorants.
• Academic and R&D: A valuable tool for methodological studies in organic chemistry, including ring-forming reactions and stereoselective transformations.

Basic Information

Product Name	Spiro[3.4]Octan-5-Ol, 6,6-Dimethyl- (9Ci)
CAS No.	820222-45-5
Molecular Formula	C10H18O
Molecular Weight	154.25 g/mol
Synonyms	6,6-Dimethylspiro[3.4]octan-5-ol; 5-Spiro[3.4]octanol, 6,6-dimethyl-; 6,6-Dimethyl-5-spiro[3.4]octanol; 6,6-Dimethylspiro[3.4]octan-5-ol (9CI); Spiro[3.4]octan-5-ol, 6,6-dimethyl-; 820222-45-5; 6,6-Dimethyl-5-hydroxy-spiro[3.4]octane
EINECS	Contact for details

Quality Control

Our Spiro[3.4]Octan-5-Ol, 6,6-Dimethyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters including assay (by GC/HPLC), chiral purity (if applicable), and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediates, ensuring reliability for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). For long-term storage under an inert atmosphere (nitrogen or argon) is recommended to maintain product integrity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (GC or HPLC)	≥ 97.0%
Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.