Description

Bicyclo[3.2.1]Octane-6-Carboxylic Acid, 1,6-Dimethyl-8-Oxo-, Methyl Ester, (1R,5S,6S)-Rel- (9Ci) is a high-purity, stereochemically defined bicyclic compound that serves as a critical advanced pharmaceutical intermediate and chiral building block for complex organic synthesis. Its unique, rigid molecular framework is essential for constructing bioactive molecules with precise three-dimensional architecture. This compound is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams developing new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially for central nervous system (CNS) and antiviral therapeutics.
• Asymmetric Synthesis: Employed as a sophisticated building block in stereoselective synthesis to introduce complex, polycyclic motifs into target molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to explore new chemical space and improve drug-like properties.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Academic & Industrial R&D: Utilized in chemical biology and organic methodology research for developing new synthetic transformations.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Bicyclo[3.2.1]Octane-6-Carboxylic Acid, 1,6-Dimethyl-8-Oxo-, Methyl Ester, (1R,5S,6S)-Rel- (9Ci)
CAS No.	819793-70-9
Molecular Formula	C12H18O3
Molecular Weight	210.27 g/mol
Synonyms	(1R,5S,6S)-rel-1,6-Dimethyl-8-oxobicyclo[3.2.1]octane-6-carboxylic acid methyl ester; Methyl (1R,5S,6S)-rel-1,6-dimethyl-8-oxobicyclo[3.2.1]octane-6-carboxylate; Bicyclo[3.2.1]octane-6-carboxylic acid, 1,6-dimethyl-8-oxo-, methyl ester, (1R,5S,6S)-rel-; 819793-70-9; (rel)-(1R,5S,6S)-1,6-Dimethyl-8-oxobicyclo[3.2.1]octane-6-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Bicyclo[3.2.1]Octane-6-Carboxylic Acid, 1,6-Dimethyl-8-Oxo-, Methyl Ester, (1R,5S,6S)-Rel- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization using HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality systems are designed to support cGMP requirements for advanced intermediates, ensuring traceability and consistency for critical pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging. Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.