Description

(4S)-2-Bromo-6-(4-Isopropyl-4,5-Dihydro-Oxazol-2-Yl)Pyridine is a high-value, chiral building block featuring a bromopyridine core fused with an isopropyl-substituted oxazoline moiety. This compound is critical for enabling the synthesis of complex, stereochemically defined molecules, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of small-molecule drug candidates, especially in kinase inhibitor and antiviral research.
• Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in asymmetric catalysis (e.g., for cross-coupling or hydrogenation reactions).
• Agrochemical Research: Used in the discovery and synthesis of novel, optically active crop protection agents and pesticides.
• Material Science: Potential building block for creating functionalized, nitrogen-containing heterocycles used in advanced organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(4S)-2-Bromo-6-(4-Isopropyl-4,5-Dihydro-Oxazol-2-Yl)Pyridine
CAS No.	819083-98-2
Molecular Formula	C11H13BrN2O
Molecular Weight	269.14 g/mol
Synonyms	(4S)-2-Bromo-6-(4-isopropyl-4,5-dihydro-1,3-oxazol-2-yl)pyridine; 2-Bromo-6-[(4S)-4-(1-methylethyl)-4,5-dihydro-1,3-oxazol-2-yl]pyridine; (S)-2-Bromo-6-(4-isopropyl-4,5-dihydrooxazol-2-yl)pyridine; 2-Bromo-6-[(4S)-4-isopropyl-4,5-dihydrooxazol-2-yl]pyridine; Bromopyridine-oxazoline chiral ligand precursor; (S)-2-(6-Bromopyridin-2-yl)-4-isopropyl-4,5-dihydrooxazole
EINECS	Contact for details

Quality Control

Our production of (4S)-2-Bromo-6-(4-Isopropyl-4,5-Dihydro-Oxazol-2-Yl)Pyridine adheres to stringent quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is fully characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profile is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.