Description

4-(tert-Butyl)-2-(Chloromethyl)Nicotinonitrile is a versatile and high-value pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a chloromethyl group and a nitrile moiety, makes it an essential building block for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Building block for developing new-generation herbicides and fungicides with enhanced efficacy and selectivity.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate for creating functionalized polymers and advanced organic electronic materials.
• Chemical Biology: Serves as a probe or linker molecule in bioconjugation and proteomics research.
• Custom Synthesis: Foundation for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.

Basic Information

Product Name	4-(tert-Butyl)-2-(Chloromethyl)Nicotinonitrile
CAS No.	817555-69-4
Molecular Formula	C11H13ClN2
Molecular Weight	208.69 g/mol
Synonyms	4-tert-Butyl-2-(chloromethyl)nicotinonitrile; 2-(Chloromethyl)-4-(tert-butyl)nicotinonitrile; 4-(1,1-Dimethylethyl)-2-(chloromethyl)-3-pyridinecarbonitrile; Nicotinonitrile, 4-(1,1-dimethylethyl)-2-(chloromethyl)-; 817555-69-4; 4-tert-Butyl-2-chloromethyl-3-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 4-(tert-Butyl)-2-(Chloromethyl)Nicotinonitrile is produced and tested under strict quality management systems to ensure consistency and reliability for research and development applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.