Description

Methyl 3-(Bromomethyl)-5-Fluorobenzoate is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. This compound is specifically engineered to serve as a key intermediate in the development of complex, biologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and production of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom and bromomethyl group enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of advanced polymers and liquid crystals, where its aromatic and halogenated structure contributes to specific material properties.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	Methyl 3-(Bromomethyl)-5-Fluorobenzoate
CAS No.	816449-87-3
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	3-(Bromomethyl)-5-Fluorobenzoic Acid Methyl Ester; Methyl 5-Fluoro-3-(bromomethyl)benzoate; 5-Fluoro-3-(bromomethyl)benzoic Acid Methyl Ester; Benzoic acid, 3-(bromomethyl)-5-fluoro-, methyl ester; Methyl 3-Bromomethyl-5-fluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 3-(Bromomethyl)-5-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.