Description

Cyclopentanecarboxylic Acid, 2-Amino-3-Ethyl-, 1,1-Dimethylethyl Ester, (1S,2R,3S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its complex, functionalized cyclopentane core, which serves as a critical precursor for constructing sophisticated molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where specific three-dimensional structure is crucial for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in areas requiring complex cyclic structures.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the specific stereochemistry can influence efficacy and environmental profile.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & Institutional Research: Utilized in university and institutional labs for methodological studies in synthetic organic chemistry and medicinal chemistry programs.
• Process Chemistry Development: Acts as a starting material for scaling up synthetic routes from laboratory to pilot plant and commercial production.

Basic Information

Product Name	Cyclopentanecarboxylic Acid, 2-Amino-3-Ethyl-, 1,1-Dimethylethyl Ester, (1S,2R,3S)- (9Ci)
CAS No.	816444-36-7
Molecular Formula	C12H23NO2
Molecular Weight	213.32 g/mol
Synonyms	(1S,2R,3S)-2-Amino-3-ethylcyclopentanecarboxylic acid tert-butyl ester; tert-Butyl (1S,2R,3S)-2-amino-3-ethylcyclopentanecarboxylate; (1S,2R,3S)-2-Amino-3-ethyl-1-cyclopentanecarboxylic acid 1,1-dimethylethyl ester; 2-Amino-3-ethylcyclopentanecarboxylic acid tert-butyl ester, (1S,2R,3S)-; Chiral cyclopentane amino ester; BOC-protected cyclopentane amino acid derivative (common functional description).
EINECS	Contact for details

Quality Control

Our production of this advanced chiral intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high stereochemical purity. Each lot is characterized using advanced analytical techniques including Chiral HPLC and NMR to confirm identity, enantiomeric excess, and chemical purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development under cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.