Description

Cyclopentanecarboxylic Acid, 2-Amino-3-Ethyl-, 1,1-Dimethylethyl Ester, (1R,2S,3R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters because its unique cyclopentane scaffold and protected amino acid functionality make it a critical intermediate for constructing complex, biologically active molecules with precise three-dimensional architecture. Pharmaceutical research and development organizations need this specific enantiomer to streamline the synthesis of novel drug candidates, particularly in therapeutic areas requiring high stereochemical fidelity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of protease inhibitors, neuraminidase inhibitors, and other small-molecule therapeutics.
• Agrochemical Research: Building block for novel, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Peptidomimetics: Used in the design and synthesis of peptide analogs and constrained peptidomimetics to improve metabolic stability and bioavailability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and organocatalysts.
• Academic & Contract Research: Essential for methodological studies in organic chemistry, particularly in stereoselective synthesis and natural product total synthesis.
• Bioconjugation Chemistry: The protected amino and ester groups provide handles for selective chemical modifications in bioconjugate and probe development.

Basic Information

Item	Details
Product Name	Cyclopentanecarboxylic Acid, 2-Amino-3-Ethyl-, 1,1-Dimethylethyl Ester, (1R,2S,3R)- (9Ci)
CAS No.	816444-28-7
Molecular Formula	C12H23NO2
Molecular Weight	213.32 g/mol
Synonyms	(1R,2S,3R)-2-Amino-3-ethylcyclopentanecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl (1R,2S,3R)-2-amino-3-ethylcyclopentanecarboxylate; (1R,2S,3R)-2-Amino-3-ethyl-1-cyclopentanecarboxylic acid tert-butyl ester; (1R,2S,3R)-2-Amino-3-ethylcyclopentane-1-carboxylic acid tert-butyl ester; (1R,2S,3R)-tert-Butyl 2-amino-3-ethylcyclopentane-1-carboxylate; 2-Amino-3-ethylcyclopentanecarboxylic acid tert-butyl ester, (1R,2S,3R)-; (1R,2S,3R)-2-Amino-3-ethyl-cyclopentanecarboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Every batch of our Cyclopentanecarboxylic Acid, 2-Amino-3-Ethyl-, 1,1-Dimethylethyl Ester, (1R,2S,3R)- (9Ci) is produced under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, chiral analysis, and NMR to ensure identity, purity, and enantiomeric excess meet the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.