Description

2-Pyrrolidinemethanol, α,α-Dimethyl-, Hydrochloride (1:1), (2R)- is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. This compound matters for its role in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) where stereochemical purity is critical. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in advanced organic synthesis and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, including central nervous system (CNS) drugs.
• Asymmetric Synthesis: Used as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce enantioselectivity.
• Agrochemical Research: Serves as a building block for developing enantiomerically pure pesticides and herbicides.
• Academic & R&D: Employed in medicinal chemistry programs and methodological studies for constructing nitrogen-containing heterocycles.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals requiring high stereochemical fidelity.

Basic Information

Product Name	2-Pyrrolidinemethanol, α,α-Dimethyl-, Hydrochloride (1:1), (2R)-
CAS No.	816425-22-6
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	(2R)-2-(Dimethylaminomethyl)pyrrolidine hydrochloride; (R)-2-(Dimethylaminomethyl)pyrrolidine HCl; (R)-N,N-Dimethyl-2-pyrrolidinemethanamine hydrochloride; (R)-2-Pyrrolidinemethanol, α,α-dimethyl-, hydrochloride; (R)-Proline dimethylamide hydrochloride; (2R)-1-(Dimethylaminomethyl)pyrrolidine hydrochloride; (R)-DMAPM hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinemethanol, α,α-Dimethyl-, Hydrochloride (1:1), (2R)- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.