Description

3-Piperidinemethanol,2-(4-Fluoro-2-Methylphenyl)-(9Ci) is a specialized piperidine derivative and a key chiral building block in advanced organic synthesis. This compound matters for its role as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals. Pharmaceutical R&D and fine chemical manufacturers need this high-purity intermediate to create novel therapeutic agents and complex molecular structures.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its specific stereochemistry can influence biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials requiring specific functional groups.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in pharmaceutical laboratories.
• Academic and Industrial R&D: A valuable reagent for medicinal chemistry programs and process chemistry optimization in both university and corporate settings.

Basic Information

Product Name	3-Piperidinemethanol,2-(4-Fluoro-2-Methylphenyl)-(9Ci)
CAS No.	815631-78-8
Molecular Formula	C13H18FNO
Molecular Weight	223.29 g/mol
Synonyms	2-(4-Fluoro-2-methylphenyl)-3-piperidinemethanol; (2R,3S)-2-(4-Fluoro-2-methylphenyl)-3-piperidinemethanol; 2-(4-Fluoro-2-methylphenyl)piperidin-3-ylmethanol; 3-Piperidinemethanol, 2-(4-fluoro-2-methylphenyl)-, (2R,3S)-rel-; 815631-78-8; A potential intermediate for Solithromycin; Cethromycin intermediate
EINECS	Contact for details

Quality Control

Our 3-Piperidinemethanol,2-(4-Fluoro-2-Methylphenyl)-(9Ci) is manufactured under strict quality management systems. We provide material that meets the stringent requirements for pharmaceutical intermediate applications, with purity typically exceeding 98.0% (by HPLC). Certificates of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles are available upon request for every batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.