Description

6-Bromo-4H-Spiro[Benzo[D][1,3]Dioxine-2,4'-Piperidine] is a high-value, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is essential for medicinal chemistry research and development, serving as a critical building block for synthesizing novel drug candidates. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and biotechnology industries for creating complex molecules targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs), particularly for CNS-targeting drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its spirocyclic and piperidine motifs.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to introduce functionalized spirocyclic frameworks into target molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines for global clients.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	6-Bromo-4H-Spiro[Benzo[D][1,3]Dioxine-2,4'-Piperidine]
CAS No.	815580-04-2
Molecular Formula	C13H16BrNO2
Molecular Weight	298.18 g/mol
Synonyms	6-Bromo-4H-spiro[benzo[d][1,3]dioxine-2,4'-piperidine]; 6-Bromo-4H-1,3-benzodioxine-2,4'-piperidine, 4'H-spiro-; 6-Bromospiro[1,3-benzodioxole-2,4'-piperidine]; 815580-04-2; Spiro[benzo[1,3]dioxole-2,4'-piperidine], 6-bromo-; 6-Bromo-4'H-spiro[1,3-benzodioxole-2,4'-piperidine]
EINECS	Contact for details

Quality Control

Our 6-Bromo-4H-Spiro[Benzo[D][1,3]Dioxine-2,4'-Piperidine] is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and pre-clinical development stages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.