Description

(E)-2,2'-(3,3-Dimethylbut-1-Ene-1,2-Diyl)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane) CAS NO 815575-36-1 is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound is a critical intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily used by R&D chemists and process development scientists for constructing carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, especially in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific stereochemistry.
• Material Science Research: Precursor for creating organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boron reagent for palladium-catalyzed coupling reactions to form biaryl and other complex structures.
• Chemical Biology Probes: Enables the synthesis of tagged molecules for studying biological pathways and protein interactions.
• Academic & Industrial R&D: Fundamental reagent for methodological development and exploring new synthetic routes in organic chemistry.

Basic Information

Item	Detail
Product Name	(E)-2,2'-(3,3-Dimethylbut-1-Ene-1,2-Diyl)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane)
CAS No.	815575-36-1
Molecular Formula	C22H40B2O4
Molecular Weight	390.17 g/mol
Synonyms	(E)-3,3-Dimethyl-1,2-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-1-ene; 1,1'-(1E)-3,3-Dimethyl-1-buten-1,2-diylbis[4,4,5,5-tetramethyl-1,3,2-dioxaborolane]; Pinacol (E)-3,3-dimethyl-1,2-bis(boronate); (E)-3,3-Dimethylbut-1-ene-1,2-diylbis(boronic acid) bis(pinacol ester); (E)-1,2-Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,3-dimethylbut-1-ene; (E)-3,3-Dimethyl-1,2-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-butene
EINECS	Contact for details

Quality Control

Our (E)-2,2'-(3,3-Dimethylbut-1-Ene-1,2-Diyl)Bis(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including NMR, HPLC, and GC to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.