Description

5-Bromo-2-Hydroxy-4,6-Dimethyl-Nicotinonitrile is a versatile and highly functionalized pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic placement of bromine and nitrile groups, which enable a wide range of coupling and functional group transformations for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, catalysts, and functional polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions due to the reactive bromine substituent.
• Academic & R&D: A valuable reagent for methodological studies and exploring new synthetic pathways in university and industrial research laboratories.

Basic Information

Product Name	5-Bromo-2-Hydroxy-4,6-Dimethyl-Nicotinonitrile
CAS No.	814262-90-3
Molecular Formula	C8H7BrN2O
Molecular Weight	227.06 g/mol
Synonyms	5-Bromo-2-hydroxy-4,6-dimethylnicotinonitrile; 5-Bromo-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carbonitrile; 3-Cyano-5-bromo-4,6-dimethyl-2-pyridone; 5-Bromo-4,6-dimethyl-2-pyridone-3-carbonitrile; 2-Hydroxy-5-bromo-4,6-dimethyl-3-cyanopyridine; 5-Bromo-2-hydroxy-4,6-dimethyl-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Hydroxy-4,6-Dimethyl-Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.