Description

4H-Imidazo[4,5-D]Pyridazin-4-One,2-Bromo-1,5-Dihydro-7-Methyl-(9Ci) CAS NO 813462-81-6 is a high-purity, advanced pharmaceutical intermediate belonging to the imidazopyridazine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) therapeutic research. It is essential for medicinal chemistry research, process development, and scale-up manufacturing within the pharmaceutical and biotechnology industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially kinase inhibitors and other enzyme-targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Process Chemistry & Scale-Up: Serves as a defined starting material for the development and validation of robust, scalable synthetic routes under GMP conditions.
• Oncology Drug Development: Integral to the research and production of novel anti-cancer agents due to the imidazopyridazine scaffold's biological relevance.
• Biochemical Research: Employed as a reference standard or probe compound in biochemical assays and target validation studies.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for client-specific drug development projects.

Basic Information

Product Name	4H-Imidazo[4,5-D]Pyridazin-4-One,2-Bromo-1,5-Dihydro-7-Methyl-(9Ci)
CAS No.	813462-81-6
Molecular Formula	C7H5BrN4O
Molecular Weight	241.05 g/mol
Synonyms	2-Bromo-1,5-dihydro-7-methyl-4H-imidazo[4,5-d]pyridazin-4-one; 2-Bromo-7-methyl-1,5-dihydro-4H-imidazo[4,5-d]pyridazin-4-one; 813462-81-6; 4H-Imidazo[4,5-d]pyridazin-4-one, 2-bromo-1,5-dihydro-7-methyl-; 2-Bromo-7-methylimidazo[4,5-d]pyridazin-4(5H)-one; 2-Bromo-7-methyl-4,5-dihydroimidazo[4,5-d]pyridazin-4-one
EINECS	Contact for details

Quality Control

Every batch of 4H-Imidazo[4,5-D]Pyridazin-4-One,2-Bromo-1,5-Dihydro-7-Methyl-(9Ci) is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and pre-clinical development. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the compound's integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.