Description

5,8,11,14-Tetraoxa-2-Azahexadecanoic Acid,16-Amino-,1,1-Dimethyl Ester is a specialized bifunctional organic compound featuring both an amino group and a protected carboxylic acid ester within a polyether chain. This unique structure makes it a valuable building block and linker molecule for advanced chemical synthesis, particularly in the development of functional materials and bioactive molecules. It is primarily utilized by pharmaceutical researchers, polymer chemists, and material scientists for applications requiring precise molecular architecture and conjugation.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for constructing drug candidates, especially those requiring polyether-amine linkers for solubility or targeting.
• Polymer Modification: Used to introduce amino-functional side chains into polymer backbones for creating specialty resins, coatings, and adhesives with enhanced properties.
• Bioconjugation Reagent: Acts as a heterobifunctional crosslinker for coupling biomolecules (e.g., proteins, peptides) to other organic molecules, nanoparticles, or surfaces.
• Dendrimer and Macromolecule Synthesis: A fundamental monomer for the iterative construction of complex, branched macromolecular structures.
• Surface Functionalization: Employed to graft amino-reactive groups onto inorganic or polymeric surfaces to alter wettability, adhesion, or biocompatibility.
• Chelating Agent Precursor: The polyether and amino motifs can be further derivatized to create ligands for metal ion complexation.
• Research & Development: A versatile tool in academic and industrial R&D for exploring new chemical entities and material properties.

Basic Information

Product Name	5,8,11,14-Tetraoxa-2-Azahexadecanoic Acid,16-Amino-,1,1-Dimethyl Ester
CAS No.	811442-84-9
Molecular Formula	C15H31NO7
Molecular Weight	337.41 g/mol
Synonyms	16-Amino-5,8,11,14-tetraoxa-2-azahexadecanoic acid 1,1-dimethyl ester; 2-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]-N-(methoxycarbonyl)-N-methylacetamide; Amino-PEG4-acetic acid, N-(methoxycarbonyl)-N-methyl-; Boc-NH-PEG4-CH2COOH (common abbreviation); Fmoc-NH-PEG4-CH2COOH (common abbreviation); PEG4-Amine-Acid Methyl Ester; Heterobifunctional PEG linker, Amino-Acid ester
EINECS	Contact for details

Quality Control

Our 5,8,11,14-Tetraoxa-2-Azahexadecanoic Acid,16-Amino-,1,1-Dimethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.