Description

1,3-Dioxaspiro[4.5]Decan-7-One,2,2,6,6-Tetramethyl-,(5S)-(9Ci) is a high-purity, stereochemically defined spirocyclic ketone derivative. This compound serves as a versatile chiral building block and advanced intermediate in sophisticated organic synthesis. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in stereoselective reactions to introduce specific chiral centers.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and plant growth regulators requiring specific stereochemistry.
• Ligand and Catalyst Development: Used in the synthesis of novel chiral ligands and organocatalysts for catalytic applications.
• Fragrance and Flavor Chemistry: Potential intermediate for creating complex, stereochemically pure odorants and flavor compounds.
• Material Science Research: Investigated as a monomer or cross-linker for specialty polymers with unique structural properties.

Basic Information

Product Name	1,3-Dioxaspiro[4.5]Decan-7-One,2,2,6,6-Tetramethyl-,(5S)-(9Ci)
CAS No.	810682-14-5
Molecular Formula	C12H20O3
Molecular Weight	212.29 g/mol
Synonyms	(5S)-2,2,6,6-Tetramethyl-1,3-dioxaspiro[4.5]decan-7-one; (5S)-2,2,6,6-Tetramethyl-1,3-dioxaspiro[4.5]decan-7-one (9CI); 1,3-Dioxaspiro[4.5]decan-7-one, 2,2,6,6-tetramethyl-, (5S)-; (S)-2,2,6,6-Tetramethyl-1,3-dioxaspiro[4.5]decan-7-one; Spirocyclic ketone derivative; (5S)-TMDK; Chiral spiroketal ketone.
EINECS	Contact for details

Quality Control

Our 1,3-Dioxaspiro[4.5]Decan-7-One,2,2,6,6-Tetramethyl-,(5S)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.