Description

Cyclohexanol, 4-Amino-, cis-, 2,2,2-Trifluoroacetate is a high-purity, functionalized cyclohexanol derivative characterized by its cis-configuration and trifluoroacetyl protecting group. This compound is a critical chiral intermediate and building block in advanced organic synthesis, offering precise stereochemical control for the development of complex molecules. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring a cis-4-aminocyclohexanol scaffold.
• Agrochemical Research: Used in the development and scale-up of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as a protected amine synthon in multi-step synthetic sequences, including peptide mimetics and complex natural product analogs.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and metal complexes.
• Material Science Precursor: Potential monomer or modifier in the synthesis of specialized polymers with tailored properties.
• Academic & Contract Research: Essential material for methodological development and discovery chemistry in academic and CRO laboratories.

Basic Information

Product Name	Cyclohexanol, 4-Amino-, cis-, 2,2,2-Trifluoroacetate
CAS No.	809288-10-6
Molecular Formula	C8H12F3NO3
Molecular Weight	227.18 g/mol
Synonyms	cis-4-Aminocyclohexyl 2,2,2-Trifluoroacetate; cis-4-Trifluoroacetamidocyclohexanol; (1r,4r)-4-(2,2,2-Trifluoroacetamido)cyclohexan-1-ol; 4-Aminocyclohexanol, cis-, Trifluoroacetate; cis-4-Aminocyclohexanol Trifluoroacetate Ester; TFA-protected cis-4-Aminocyclohexanol; (1r,4r)-4-Aminocyclohexanol Trifluoroacetic Acid Ester
EINECS	Contact for details

Quality Control

Our Cyclohexanol, 4-Amino-, cis-, 2,2,2-Trifluoroacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.